3. Arthralgia

Arthralgia refers to joint pain caused by an injury, infection, or illness. Unlike arthritis, which involves inflammation of affected joints, those infected with Zika have arthralgia, which affects smaller joints in the hands and feet. This pain typically persists longer than the duration of the fever and may be the earliest symptom to appear. Resting and taking painkillers other than NSAIDs may provide relief. Though not overly incapacitating, Zika fever with arthralgia can be uncomfortable for people with weaker constitutions.