China shocks world by genetically engineering human embryos

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Critics warned that China was becoming the ‘Wild West’ of genetic research Chinese scientists have reported that they have carried ou...


Critics warned that China was becoming the ‘Wild West’ of genetic research

Chinese scientists have reported that they have carried out the world's first experiments to genetically engineer a human embryo
Chinese scientists have reported that they have carried out the world's first experiments to genetically engineer a human embryo Photo: ALAMY


But critics warned that China was becoming the ‘Wild West’ of genetic research saying it was the first step towards designer children and called for a worldwide ban on the practice.
The work was reported in the journal Protein and Cell after the prestigious science journals Nature and Science refused to publish the study on ethical grounds.
"This news emphasises the need for an immediate global ban on the creation of GM designer babies,” said Human Genetics Alert Director, Dr David King.
“It is critical that we avoid a eugenic future in which the rich can buy themselves a baby with built-in genetic advantages.
“It is entirely unnecessary since there are already many ethical ways to avoid thalassaemia. This research is a classic example of scientific careerism - assuring one's place in the history books even though the research is unnecessary and unethical."
The team has used a gene-editing technique known as CRISPR/Cas9 which was discovered by scientists at MIT.
It works by capitalising on the fact that bacteria attack viruses by snipping away part of their genetic code, effectively dismembering the virus. The CRISPR technique uses a bacterially derived protein to cut-away a particular gene, which is then replaced or repaired by another molecule introduced at the same time.
The technique has been used in adult cells and animal models but never in human embyos.
Advocates of gene editing say that it could eradicate devastating inherited disease. But others are worried that it crosses an ethical line, allowing children to be genetically engineered. And because the genetic changes are happening to embryos the changes will be passed down to future generations.
Huang and his colleagues set out to see if the procedure could replace a gene in a single-cell fertilized human embryo; in principle, all cells produced as the embryo developed would then have the repaired gene.
The Chinese team used embryos they obtained from the fertility clinics had been created for use in IVF but had an extra set of chromosomes, following fertilization by two sperm, which stops them resulting in a live birth.
They injected 86 embryos with the Cas9 protein and left them for two days to allow the gene-editing to take place.
Of the 71 embryos that survived, 54 were genetically tested. This revealed that just 28 were successfully spliced, and only a fraction of those contained the replacement genetic material.
They also found a number of unexpected mutations in genes which should not have been effected by the technique.
British scientists said that no more experiments should be carried out until there had been an international agreement on whether the technique was safe and ethical.
Prof Shirley Hodgson, Professor of Cancer Genetics, St George’s University of London, said: “I think that this is a significant departure from currently accepted research practice. Can we be certain that the embryos that the researchers were working on were indeed non-viable?
"Any proposal to do germline genetic manipulation should be very carefully considered by international regulatory bodies before it should be considered as a serious research prospect."
Dr Philippa Brice, of the health policy think-tank the PHG Foundation, added: “This story underlines the urgent necessity for international dialogue over the ethics of germline gene editing in human embryos, well in advance of any progression towards theoretical clinical application.
"Recent calls for a moratorium on any such research to allow time for expert and public consideration of what is and is not ethically, socially and indeed legally acceptable with respect to human germline genetic modification should definitely be heeded.”
British biologist Edward Lanphier, told Nature “we need to pause this research and make sure we have a broad based discussion about which direction we are going here.”
George Daley, a stem-cell biologist at Harvard Medical School in Boston added: "The study is a landmark, as well as a cautionary tale.
"Their study should be a stern warning to any practitioner who thinks the technology is ready for testing to eradicate disease genes."
Huang said he had abandoned the current project to go back to working out how to minimise the unexpected mutations in adults cells and animals.
However at least four groups in China are believed to be currently working on genetically modifying human embryos.


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आडूबान,1,जानवरों की अभिव्यक्ति,1,जीवन और जंग,1,जीवन की उत्‍पत्ति,1,जैव विविधता वर्ष,1,जैव शवदाह,1,ज्योतिष,1,ज्योतिष और अंधविश्वास,2,झारखण्‍ड,1,टिंडल प्रभाव,1,टीलोमियर,1,टीवी और स्‍वास्‍थ्‍य,1,टीवी के दुष्‍प्रभाव,1,टेक्‍नालॉजी,1,टॉप 10 ब्लॉगर,1,डा0 अब्राहम टी कोवूर,1,डा0 ए0 पी0 जे0 अब्दुल कलाम,1,डाइनामाइट,1,डाटा सेंटर,1,डिस्कस,1,डी•एन•ए• की खोज,3,डीप किसिंग,1,डॉ मनोज पटैरिया,1,डॉ. के.एन. पांडेय,1,डॉ० मिश्र,1,ड्रग एडिक्‍ट,1,ड्रग्स,1,ड्रग्‍स की लत,1,तम्बाकू,1,तम्‍बाकू के दुष्‍प्रभाव,1,तम्बाकू निषेध,1,तर्कशास्त्र,1,ताँत्रिक क्रियाएँ,1,थर्मोइलेक्ट्रिक जेनरेटर,1,थ्री ईडियट्स के फार्मूले,1,दर्दनाशी,1,दर्शन,1,दर्शन लाल बवेजा,3,दिल की बीमारी,1,दिव्‍य शक्ति,1,दुरबीन,1,दूरानुभूति,1,दोहरे मानदण्ड,1,धरोहर,1,धर्म,2,धातु विज्ञान,1,धार्मिक पाखण्ड,1,धुम्रपान और याद्दाश्‍त,1,धुम्रपान के दुष्‍प्रभाव,1,धूल-मिट्टी,1,नई खोजें,1,नन्हे आविष्कार,1,नमक,1,नवाचारी भौतिकी,1,नशीली दवाएं,1,नाइट शिफ्ट के दुष्‍प्रभाव,1,नारायणमूर्ति,1,नारी-मुक्ति,1,नींद और बीमारियां,1,नींद न आने के कारण,1,नेत्रदान और 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पम्प,1,ब्रह्मण्‍ड,1,ब्रह्मा,1,ब्रह्माण्‍ड,1,ब्रह्माण्‍ड के रहस्‍य,1,ब्रह्मान्ड,1,ब्रेन म्‍यूजिक,1,ब्लॉग लेखन,1,ब्लॉग लेखन के द्वारा विज्ञान संचार,2,ब्लॉगिंग का महत्व,1,भारतीय आयुर्विज्ञान अनुसंधान परिषद,1,भारतीय विज्ञान कथा लेखक समिति,1,भारतीय वैज्ञानिक,2,भारतीय शोध,1,भूकंप के झटके,1,भूकम्‍प,1,भूगर्भिक हलचलें,1,मंगल,1,मधुमेह और खानपान,1,मनजीत सिंह बोपाराय,1,मनीष मोहन गोरे,1,मनीष वैद्य,1,मनु स्मृति,1,मनोरंजक गणित,1,महिला दिवस,1,माचू-पिचू,1,मानव शरीर,1,माया,1,मारिजुआना,1,मासिक धर्म,1,मिल्‍की वे,1,मिशन स्टारडस्ट-नेक्स,1,मीठी गपशप,1,मीमांसा,1,मुख कैंसर,1,मृत सागर,1,मेघ राज मित्र,1,मेडिकल रिसर्च,1,मेरी शैली,1,मैथेमेटिक्स ओलम्पियाड,1,मैरी क्‍यूरी,2,मैरीन इनोवेटिव टेक्नोलॉजीज लि,1,मोटापा,1,मोबाईल के नुकसान,1,मौसम,1,यजुर्वेद,1,युवा अनुसंधानकर्ता पुरष्कार,1,यूरी गागरिन,1,योगेन्द्र पाल,1,योगेश,1,योगेश रे,1,रक्षा उपकरण,1,राईबोसोम,1,रूप गठन,1,रेडियो टोमोग्राफिक इमेजिंग,1,रैबीज,1,रोचक रोमांचक अंटार्कटिका,4,रोबोटिक्स,1,लखनऊ,1,लादेन,1,लालन-पालन,1,लिनक्स,1,लिपरेशी,1,लीप इयर,1,लेड,1,लॉ ऑफ ग्रेविटी,1,लोक विज्ञान,1,लौह स्तम्भ,1,वजन घटाने का आसान तरीका,1,वाई गुणसूत्र,1,वायु प्रदुषण,1,वाशो,1,विज्ञान,1,विज्ञान कथा,3,विज्ञान कथा सम्मेलन,1,विज्ञान के खेल,2,विज्ञान चुटकले,1,विज्ञान तथा प्रौद्यौगिकी,1,विज्ञान प्रगति,1,विज्ञान ब्लॉग,1,विज्ञापन,1,विटामिनों के वहम,1,विद्युत,1,विवेकानंद,1,विवेचना-व्याख्या,1,विश्व नि-तम्बाकू दिवस,1,विश्व पर्यावरण दिवस,1,विश्व भूगर्भ जल दिवस,1,विष्णु,1,वीडियो,1,वीडियो बुक,1,वैज्ञानिक दृष्टिकोण,1,वैद्य अश्विनी कुमार,1,वोस्तोक,1,व्‍यायाम के लाभ,1,व्हेलॉसिटी,1,शिव,1,शुक्र पारगमन,1,शुगर के दुष्‍प्रभाव,1,शून्य,1,शोध परिणाम,1,शोधन,1,श्रृष्टि का अंत,1,सं. राष्ट्रसंघ,1,सकारात्‍मक सोच का जादू,1,संक्रमण,1,संख्या,1,संजय ग्रोवर,1,संज्ञात्मक पक्षी विज्ञान,1,सटीक व्‍यायाम,1,संत बलबीर सिंह सीचेवाल,1,सत्यजित रे,1,समय की बरबादी को रोचकने के उपाय,1,समाज और हम,1,समुद्र,1,संयोग,1,सर चन्द्रशेखर वेंकट रमन राष्ट्रीय विज्ञान दिवस,1,सर्प संसार,1,साइकोलोजिस्ट,1,साइनस उपचार,1,साइंस ब्लागर्स मीट,1,साइंस ब्लागर्स मीट.,2,साइंस ब्लॉग कार्यशाला,2,साइंस ब्लॉगर्स असोसिएशन अवार्ड,1,साइंस ब्लॉगर्स असोसिएशन रजिस्ट्रेशन,1,साइंस ब्लॉगर्स ऑफ दि ईयर अवार्ड,1,साइंस ब्लोगिंग,1,साईकिल,1,सामवेद,1,सामाजिक अभिशाप,1,सामाजिक चेतना,1,साहित्यिक चोरी,2,सिगरेट छोड़ें,1,सी. एस. आई. आर.,1,सी.वी.रमण विज्ञान क्लब,1,सीजेरियन ऑपरेशन,1,सुपर अर्थ,1,सुपर कम्प्यूटर,1,सुरक्षित ब्लॉगिंग,1,सूर्यग्रहण,2,सृष्टि व जीवन,3,सेक्स रेशियो,1,सेहत की देखभाल,1,सोशल नेटवर्किंग,1,स्टीफेन हाकिंग,1,स्पेन,1,स्मृति,1,स्वर्ण अनुपात,1,स्वाईन-फ्लू,1,स्वास्थ्य,2,स्‍वास्‍थ्‍य और खानपान,1,स्वास्थ्य चेतना,3,हमारे वैज्ञानिक,4,हरित क्रांति,1,हंसी के फायदे,1,हाथरस कार्यशाला,1,हिंद महासागर,1,हृदय रोग,1,होलिका दहन,1,ह्यूमन रोबोट,1,
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Science Bloggers' Association of India: China shocks world by genetically engineering human embryos
China shocks world by genetically engineering human embryos
https://secure.i.telegraph.co.uk/multimedia/archive/02565/EGG_2565177b.jpg
Science Bloggers' Association of India
https://blog.scientificworld.in/2018/11/china-shocks-world-by-genetically.html
https://blog.scientificworld.in/
https://blog.scientificworld.in/
https://blog.scientificworld.in/2018/11/china-shocks-world-by-genetically.html
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